Pathogenesis of acute renal failure.
نویسندگان
چکیده
منابع مشابه
Pathogenesis of oliguria in acute renal failure.
• Nearly half a century has passed since Dr. A. N. Richards described his findings of continued glomerular filtration in a frog made anuric with HgCl2 (1). Although his concept that nearly all of the glomerular filtrate passively moves across damaged tubular epithelial cells was given support by the microdissection studies of Dr. Jean Oliver et al. (2), the intervening years have not seen a con...
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Acute renal failure (ARF), characterized by sudden loss of the ability of the kidneys to excrete wastes, concentrate urine, conserve electrolytes, and maintain fluid balance, is a frequent clinical problem, particularly in the intensive care unit, where it is associated with a mortality of between 50% and 80%. In this review, the epidemiology and pathophysiology of ARF are discussed, including ...
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In this study, we characterized the sequence of several intrarenal events and evaluated their relative importance in the pathogenesis of unilateral oliguric acute renal failure induced experimentally in rats by complete occlusion of a renal artery for 1 hour. Kidneys were studied prior to occlusion and 1-3 hours and 22-26 hours after release of the temporary occlusion. Renal blood flow measured...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.280.6209.254-c